diff --git a/arcade/arcade/core/catalog.py b/arcade/arcade/core/catalog.py
index 4602a930..5ea7042a 100644
--- a/arcade/arcade/core/catalog.py
+++ b/arcade/arcade/core/catalog.py
@@ -118,10 +118,12 @@ class ToolCatalog(BaseModel):
     _tools: dict[FullyQualifiedName, MaterializedTool] = {}
 
     _disabled_tools: set[str] = set()
+    _disabled_toolkits: set[str] = set()
 
     def __init__(self, **data) -> None:  # type: ignore[no-untyped-def]
         super().__init__(**data)
         self._load_disabled_tools()
+        self._load_disabled_toolkits()
 
     def _load_disabled_tools(self) -> None:
         """Load disabled tools from the environment variable.
@@ -145,6 +147,23 @@ class ToolCatalog(BaseModel):
 
             self._disabled_tools.add(tool.lower())
 
+    def _load_disabled_toolkits(self) -> None:
+        """Load disabled toolkits from the environment variable.
+
+        The ARCADE_DISABLED_TOOLKITS environment variable should contain a
+        comma-separated list of toolkits that are to be excluded from the
+        catalog.
+
+        The expected format for each disabled toolkit is:
+        - [CamelCaseToolkitName]
+        """
+        disabled_toolkits = os.getenv("ARCADE_DISABLED_TOOLKITS", "").strip().split(",")
+        if not disabled_toolkits:
+            return
+
+        for toolkit in disabled_toolkits:
+            self._disabled_toolkits.add(toolkit.lower())
+
     def add_tool(
         self,
         tool_func: Callable,
@@ -183,6 +202,10 @@ class ToolCatalog(BaseModel):
             logger.info(f"Tool '{fully_qualified_name!s}' is disabled and will not be cataloged.")
             return
 
+        if str(toolkit_name).lower() in self._disabled_toolkits:
+            logger.info(f"Toolkit '{toolkit_name!s}' is disabled and will not be cataloged.")
+            return
+
         self._tools[fully_qualified_name] = MaterializedTool(
             definition=definition,
             tool=tool_func,
@@ -208,6 +231,10 @@ class ToolCatalog(BaseModel):
         Add the tools from a loaded toolkit to the catalog.
         """
 
+        if str(toolkit).lower() in self._disabled_toolkits:
+            logger.info(f"Toolkit '{toolkit.name!s}' is disabled and will not be cataloged.")
+            return
+
         for module_name, tool_names in toolkit.tools.items():
             for tool_name in tool_names:
                 try:
diff --git a/arcade/tests/core/test_catalog.py b/arcade/tests/core/test_catalog.py
index 45eb2524..a2a0bb7a 100644
--- a/arcade/tests/core/test_catalog.py
+++ b/arcade/tests/core/test_catalog.py
@@ -180,3 +180,18 @@ def test_add_tool_with_whitespace_disabled_tools(monkeypatch):
     catalog = ToolCatalog()
     catalog.add_tool(sample_tool, "SampleToolkitOne")
     assert len(catalog._tools) == 1
+
+
+def test_add_tool_with_disabled_toolkit(monkeypatch):
+    monkeypatch.setenv("ARCADE_DISABLED_TOOLKITS", "SampleToolkitOne")
+    catalog = ToolCatalog()
+
+    catalog.add_toolkit(
+        Toolkit(
+            name="SampleToolkitOne",
+            package_name="sample_toolkit_one",
+            version="1.0.0",
+            description="A sample toolkit",
+        )
+    )
+    assert len(catalog._tools) == 0